The Czech Technical University in Prague (CTU) founded the Czech Institute of Informatics, Robotics and Cybernetics (CIIRC) in July 2013. The institute’s purpose is to effectively integrate research in computer science, robotics and cybernetics within CTU, especially research in the fields of intelligent, distributed and complex systems, automatic control, computer-aided manufacturing, bioinformatics, biomedicine and assistive technologies, while also raising the level of the existing cooperation between CTU, the Academy of Sciences of the Czech Republic and the most important universities in the Czech Republic and abroad. The aim is to create a motivating environment for the support of business and innovation activities of students and researchers by employing the latest knowledge and experience of technology transfer in the world’s top incubators (Silicon Valley, Cambridge, Oxford, Israel, Singapore). CIIRC will also offer suitable facilities for the presence of global companies and create conditions for long-term co-funding of research conducted by major international companies, many of which (Siemens, Rockwell Automation, and Eaton, among others) have already expressed interest in being present in CIIRC.