The Institute of Molecular and Translational Medicine (IMTM) at the Faculty of Medicine and Dentistry, Palacky University in Olomouc, was established in 2010 within an infrastructural project initiated by the Palacky University in close cooperation with the University Hospital in Olomouc, the Institute of Chemical Technology and the Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic in Prague. The research conducted at IMTM is focused on better understanding of human diseases and development of future medicines and diagnostics. IMTM’s research is organised in six research programmes that integrate activities across individual departments/laboratories and research groups: Molecular Basis of Disease, Medicinal Chemistry, Chemical Biology and Experimental Therapeutics, Biomarkers – Identification and Validation, Pharmacology and Toxicology, and Translational Medicine. Furthermore, research at the Laboratory of Experimental Medicine focuses on human disease, development of innovative therapeutics, biomarkers and in vitro/in vivo diagnostics. The Genome Integrity Laboratory conducts research focused on various mechanistic aspects of the DNA damage response and DNA repair pathways.